1999.09 - 2003.07 华中科技大学 光电子工程系  本科
2003.09 - 2006.07 华中科技大学 生物医学工程系  硕士
2008.09 - 2011.07 华中科技大学 生物医学工程系  博士

摄食是动物和人获取能量和营养的唯一方式，吃多吃少决定了机体的健康，对体重，代谢，免疫，甚至寿命都有非常重要的影响。神经系统在摄食和代谢调控中占据主导地位。我们实验室将从神经系统如何感知机体营养状态；如何调控摄食行为；如何基于机体的营养状态调控代谢、免疫和寿命等几个方面着手，研究神经调控摄食的机制及对健康的影响。研究方向主要归纳为如下两点：
　　1）神经调控摄食和能量代谢的机制。
　　2）神经-免疫-代谢的反馈调节机制。

2011.07 - 2020.12 北京生命科学研究所 影像中心  主任
2021.01 - 至今 中国科学技术大学生医部  特任教授

先后获得国家自然科学基金优秀青年基金(2018年)，面上基金(2023年)，科技部“科技创新2030-脑科学重大项目”（2021年），中科院百人计划（2022年）等项目支持。

Key Research Publications (# Corresponding author)
1、Jing Cai, Jing Chen, Joshua Ortiz-Guzman, Jessica Huang, Benjamin R Arenkiel, Yuchen Wang, Yan Zhang, Yuyan Shi, Qingchun Tong#, Cheng Zhan#. AgRP neurons are not indispensable for body weight maintenance in adult mice. Cell Reports (2023).
2、Jing Chen, Chunli Li, Zhonghua Lu, Cheng Zhan#. Optimal Timing of a Commonly-Used Rabies Virus for Neural Recording and Manipulation. Neuroscience Bulletin（2022）. doi.org/10.1007/s12264-022-00819-8.
3、Jing Chen, Minxiu Cheng, Liang Wang, Lei Zhang, Dan Xu, Peng Cao, Fengchao Wang, Herbert Herzog, Sen Song, Cheng Zhan#. A vagal-NTS neural pathway that stimulates feeding. Current Biology（2020）. 
4、L. Mei, Y.Fan , M. Wang, X. Lv , C. Zhan#, E. Zhang#. Longitudinal in vivo recording of clock gene transcription in the brains of freely-moving mice. PNAS (2018).
5、L. Mei , C. Zhan , E. Zhang. In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters. JOVE (2018).
6、Z. Zhao, L. Wang, W. Gao, F. Hu, J. Zhang, Y. Ren, R. Lin, Q. Feng, M. Cheng, D. Ju, Q. Chi, D. Wang, S. Song, M. Luo and C. Zhan# (2017). A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress. Neuron 95, 138-152 e135. Featured Article. 
7、D. Wang, X. He, Z. Zhao, Q.Feng, R.Lin, Y. Sun, T. Ding, F. Xu #, M. Luo #, C. Zhan # (2015) Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons. Frontiers in Neuroanatomy 9:40.
8、C. Zhan*#, J. Zhou *, Q. Feng, J. Zhang, S. Lin, J. Bao, P. Wu, M. Luo #, Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. J Neurosci 33:3624-3632, 2013. Selected for F1000Prime.
9、C. Zhan, M. Luo, Diverse patterns of odor representation by neurons in the anterior piriform cortex of awake mice. J Neurosci 30, 16662-16672, 2010.
Reviews and Invited book chapters
1、Jing Chen, Cheng Zhan#. Gut–vagus–NTS neural pathway in controlling feeding behaviors. Stress and Brain, 2023
2、Zeng, W.#, Yang, F.#, Shen, W.L.#, Zhan, C.#, Zheng, P.#, and Hu, J. (2022). Interactions between central nervous system and peripheral metabolic organs. Sci China Life Sci 65, https://doi.org/10.1007/s11427-021-2103-5.
3、占成，摄食行为的神经调控。中国科学.生命科学，2020年。
4、Zhan C#. POMC Neurons: Feeding, Energy Metabolism, and Beyond. In Neural Regulation of Metabolism. 2018 (pp. 17-29). Springer, Singapore.
Coauthor Publications
1、Zhiyong Xie, Xianying Zhang, Miao Zhao, Lifang Huo, Meizhu Huang, Dapeng Li, Shuangfeng Zhang, Xinyu Cheng, Huating Gu, Chen Zhang, Cheng Zhan, Fengchao Wang, Congping Shang, Peng Cao (2022). The gut-to-brain axis for toxin-induced defensive responses. Cell, 2022
1、Z. Huang, L. Liu, J. Zhang, K. Conde, J. Phansalkar, Z. Li, L. Yao, Z. Xu, W. Wang, J. Zhou, G. Bi, F. Wu, R. J. Seeley, M. M. Scott, C. Zhan, Z. P. Pang and J. Liu (2022). Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism. Sci Adv, eabn5345.
2、 Zhiyong Xie, Huating Gu, Meizhu Huang, Xinyu Cheng, Congping Shang, Ting Tao, Dapeng Li, Yuan Xie, Jidong Zhao, Wei Lu, Zhibin Zhang, Cheng Zhan, Zongxiang Tang, Fan Zhang, Peng Cao. (2022). Mechanically evoked defensive attack is controlled by GABAergic neurons in the anterior hypothalamic nucleus. Nature neuroscience
3、 Koga, K., Yamada, A., Song, Q., Li, X.H., Chen, Q.Y., Liu, R.H., Ge, J., Zhan, C., Furue, H., Zhuo, M., et al. (2020). Ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex. Mol Brain 13, 49
4、Shen, E.Z., Song, C.Q., Lin, Y., Zhang, W.H., Su, P.F., Liu, W.Y., Zhang, P., Xu, J., Lin, N., Zhan, C., Wang, X., Shyr, Y., Cheng, H., and Dong, M.Q. Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans. Nature 508, 128-132. (Author contribution: live imaging)
5、Tang, Z., Hu, Y., Wang, Z., Jiang, K., Zhan, C., Marshall, W.F., and Tang, N. (2018). Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis. Dev Cell (Author contribution: 2-photon imaging)
6、Mengxiao Yu, Fuyou Li, Zhigang Chen, He Hu, C. Zhan, Hong Yang and Chunhui Huang, Laser Scanning Up-Conversion Luminescence Microscopy for Imaging Cells Labeled with Rare-Earth Nanophosphors, Anal. Chem. 2009, 81(3), 930–935. (Author contribution: 2-photon imaging)