1999.9—2004.7   中国科学技术大学化学物理专业   本科生

2004.8—2010.2   美国印第安纳大学物理化学专业   博士研究生  

1.生物信息学、计算生物学和生物大数据分析软件开发

2.单细胞测序技术及空间转录组技术开发

3.精准医学与肿瘤个性化调控机制

2009.8—2010.5   美国希望之城医院贝克曼癌症研究中心 生物信息专家

2010.6—2016.5   美国斯坦福大学 生物信息专家、高级研究员、生物信息中心主任

2016.6 至今         中国科学技术大学生命科学学院    教授

2019.7—2020.6   中国科学技术大学国际合作与交流部  副部长（主持工作）

2020.7—2021.6   中国科学技术大学国际合作与交流部  部长  

2021.6—至今       中国科学技术大学国际合作与交流部部长兼港澳台办公室主任 

2020年，中国科学技术大学，海外校友基金会“青年教师事业奖”。

2021年，国家自然科学基金委，杰出青年基金项目。

1. 国家自然科学基金委杰出青年项目，  400 万， 2 022.01-2026.12 ，主持；   

2 .RNA动态结构及多维相互作用研究，国自然基金委重大研究计划集成项目，100万，2020.01-2022.12，主持; 
   
3 .神经系统干细胞谱系分化命运决定新技术新方法研发，科技部，360万，2020.10-2024.12，课题组长;    

4. 长链非编码  RNA 和染色质互作的系统性研究，国家自然科学基金，85万，2017.01-2019.12，主持;  
    
5. .细胞周期和细胞分裂模式对干细胞多能性维持与分化的调控机制，科技部，170万，2017.07-2021.12，参与;  
  
6 .单细胞多组学研究结合纳米材料探索胶质母细胞瘤治疗新方法，安徽省科技厅，220万，2020.10-2023.09，主持;

1.Zhuoqiao Shen*, Minghao Fang*, Wujianan Sun*, Meifang Tang, Nianping Liu, Lin Zhu, Qian Liu, Bin Li, Ruoming Sun, Yu Shi, Chuang Guo#, Jun Lin# and Kun Qu#“A transcriptome atlas and interactive analysis platform for autoimmune disease”, Database, 2022.

2.Bin Li*, Wen Zhang*, Chuang Guo*, Hao Xu, Longfei Li, Minghao Fang, Yinlei Hu, Xinye Zhang, Xinfeng Yao, Meifang Tang, Ke Liu, Xuetong Zhao, Jun Lin, Linzhao Cheng, Falai Chen, Tian Xue and Kun Qu#“Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution”, Nature Methods, 2022.

3.Chuang Guo*, Mingming Wu*, Beibei Huang*, Rui Zhao, Linlin Jin, Binqing Fu, Ping Wang, Dongyao Wang, Meijuan Zheng, Jingwen Fang, Haiming Wei#, Kun Qu# and Fang Ni#“Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19”, Genome Medicine, 2022.

4.Aimaiti Yasen*, Wujianan Sun*, Abudusalamu Aini, Tuerganaili Aji, Yingmei Shao, Hui Wang, Kun Li, Wending Li, Chuanshan Zhang, Ayifuhan Ahan, Tiemin Jiang, Zongding Wang, Wenbao Zhang, Cheng Sun, Kun Qu#, Hao Wen#“Single-Cell RNA Sequencing Reveals the Heterogeneity of Infiltrating Immune Cell Profiles in the Hepatic Cystic Echinococcosis Microenvironment”, Infection and Immunity, 2021.

5.Rendong Hu*, Wen Zhang*, Liang Li#, Zuqi Zuo, Min Ma, Jinfen Ma, Tingting Yin, Caiyue Gao, Shuhan Yang, Zhibin Zhao, Zijun Li, Guibin Qiao, Zhexiong Lian#, Kun Qu#“Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity” , Cell Death and Disease, 2021.

6. Nianping Liu*, Chen Jiang*, Pengfei Cai*, Zhuoqiao Shen, Wujianan Sun, Hao Xu, Minghao Fang, Xinfeng Yao, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jun Lin, Chuang Guo # ,  Kun Qu # , Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes,  Cell Reports , 2021.

7. Yinlei Hu* ,  Bin Li * ,  Wen Zhang ,  Nianping Liu ,  Pengfei Cai ,  Falai Chen # ,  Kun Qu # , WEDGE: imputation of gene expression values from single-cell RNA-seq datasets using biased matrix decomposition,  Briefings in Bioinformatics , 2021.

8. Xianwen Ren*, Wen Wen*, Xiaoying Fan*, Wenhong Hou*, Bin Su*,  Pengfei Cai *, Jiesheng Li*, Yang Liu*, Fei Tang*, Fan Zhang*, Yu Yang*, Jiangping He*, ……Zheng Zhang # ,  Kun Qu # , Xiaoqun Wang # , Jiekai Chen # , Ronghua Jin # , Zemin Zhang # , COVID-19 immune features revealed by a large-scale single cell transcriptome atlas,  Cell , 2021.

9. Young Li*, Kun Li*, Lianbang Zhu, Bin Li, Dandan Zong, Pengfei Cai, Chen Jiang, Pengcheng Du, Jun Lin,  Kun Qu # , Development of double-positive thymocytes at single-cell resolution,  Genome Medicine , 2021.

10. Qian Liu*, Lisa C. Zaba*, Ansuman T. Satpathy, Michelle Longmire, Wen Zhang, Kun Li, Jeffrey Granja, Chuang Guo, Jun Lin, Rui Li, Karen Tolentino, Gabriela Kania, Oliver Distler, David Fiorentino, Lorinda Chung,  Kun Qu # , Howard Y. Chang # , Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis,  Nature Communications , 2020.

11. Chuang Guo*, Bin Li*, Huan Ma, Xiaofang Wang, Pengfei Cai, Qiaoni Yu, Lin Zhu, Liying Jin, Chen Jiang, Jingwen Fang, Qian Liu, Dandan Zong, Wen Zhang, Yichen Lu, Kun Li, Xuyuan Gao, Binqing Fu, Lianxin Liu, Xiaoling Ma, Jianping Weng, Haiming Wei, Tengchuan Jin # , Jun Lin # ,  Kun Qu # , Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm,  Nature Communications , 2020.

12. Bin Li*, Young Li*, Kun Li, Lianbang Zhu, Qiaoni Yu, Pengfei Cai, Jingwen Fang, Wen Zhang, Pengcheng Du, Chen Jiang, Jun Lin,  Kun Qu # , APEC: an accesson-based method for single-cell chromatin accessibility analysis,  Genome Biology , 2020.

13. Haohuan Xie*, Wen Zhang*, Mei Zhang* # , Tasneem Akhtar, Young Li, Wenyang Yi, Xiao Sun, Zuqi Zuo, Min Wei, Xin Fang, Ziqin Yao, Kai Dong, Suijuan Zhong, Qiang Liu, Yong Shen, Qian Wu, Xiaoqun Wang, Huan Zhao, Jin Bao,  Kun Qu # , Tian Xue # , Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids,  Science Advances , 2020.

14.  Kun Qu *, Lisa C. Zaba*, Ansuman T. Satpathy, Paul G. Giresi, Rui Li, Yonghao Jin, Randall Armstrong, Chen Jin, Nathalie Schmitt, Ziba Rahbar, Hideki Ueno, William J. Greenleaf, Youn H. Kim # , Howard Y. Chang # , Chromatin accessibility landscape of cutaneous T cell lymphoma and dynamic response to HDAC inhibitors,  Cancer Cell , 2017.  

15.  Kun Qu *, Sara Garamszegi*, Felix Wu*, Helga Thorvaldsdottir, Ted Liefeld, Marco Ocana, Diego Borges-Rivera, ……Aviv Regev, Howard Y. Chang, Jill P Mesirov # , Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace,  Nature Methods , 2016.